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KMID : 0360220180590060537
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Journal of the Korean Ophthalmological Society
2018 Volume.59 No. 6 p.537 ~ p.542
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Retinal Nerve Fiber Layer Thickness Measured by Spectral Domain Optical Coherence Tomography in Healthy Koreans
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Choi Youn-A
Cho Byung-Joo
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Abstract
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Purpose: To determine normal retinal nerve fiber layer (RNFL) thickness by age and to investigate the relationships of the RNFL with clinical variables using spectral domain optical coherence tomography (SD-OCT) in healthy Koreans.
Methods: The peripapillary RNFL thicknesses were measured around the optic disc using consecutive circular B-scans with 3.5 mm diameter and automatically calculated using a SD-OCT.
Results: Three hundreds fifty-two eyes of 205 healthy subjects were included in the study and RNFL thickness were measured by SD-OCT. Overall average RNFL thickness was 100.2 ± 10.9 μm, and significantly and negatively correlated with age (r = -0.164, p = 0.002). The overall average RNFL thickness decrease per decade was 0.8 μm (95% confidence interval, -0.3 to -1.3, p = 0.019). Mean RNFL thickness of each quadrant was significantly correlated with axial length except in the superior quadrant.
Conclusions: This study describes the normal RNFL thickness values of Koreans as determined by SD-OCT. Furthermore, age was found to be correlated with normal RNFL thickness, however age-related changes were not uniform across every region.
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KEYWORD
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Axial length, Cup-to-disc ratio, Korean, Retinal nerve fiber layer, Spectral domain optical coherence tomography
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